NAD+ Shows Promise for Parkinson’s & Alzheimer’s

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Have you or someone you love been diagnosed with a debilitating degenerative condition such as Parkinson’s Disease (PD), Alzheimer’s Disease (AD), or Multiple Sclerosis (MS)? 

There are 500,000 cases of Alzheimer’s disease reported each year. Approximately 60,000 Americans are diagnosed with PD each year with more than 10 million people worldwide living with PD. Over one million Americans over the age of 18 are living with multiple sclerosis. 

Though these conditions are not necessarily reversible, there are ways to keep symptoms at bay and help the body restore cellular function as well as stopping the progression of symptoms. 

Here at SFNM, we offer an IV treatment using Nicotinamide Adenine Dinucleotide (NAD) therapy. NAD+ is a coenzyme found within every cell to help drive enzymatic reactions forward, initiating revitalization of cellular function. In addition, NAD+ also influences healthy gene expression relating to DNA repair, cell death, and certain anti-inflammatory processes.

Why does NAD+ seem to have this positive influence on neurodegenerative conditions?

For starters, every cell in each organ system of the body has a critical role. If this role is not met, the cell cannot properly function within that environment to perform its given purpose. If the DNA structure is damaged or the energy source (mitochondria), isn’t able to be produced, symptoms of disease will begin manifesting in a variety of ways. In particular, neurons are especially susceptible to energy fluctuations due to mitochondrial dysfunction. In turn, damaged neurons can lead to the pathogenesis of various neurodegenerative diseases. 

NAD+ has the ability to regulate a class of proteins known as sirtuins. Sirtuins play a vital role in regulating anti-inflammatory processes throughout the body and the brain. Many studies have linked the neuroprotective effects of sirtuins and its implications to AS, PD, MS, as well as ALS. 

NAD+ and Parkinson’s Disease

It has also been noted that NAD+ levels fluctuate in patients suffering with PD, therefore, altering the expression of sirtuins. Increased production or administering of NAD+ has been shown to promote neurogenesis (growth and development of new neurons). 

There have also been studies done revealing information regarding another class of enzymes that play a key role in DNA repair. These are called PARP—poly (ADP-Ribose) polymerase. While these enzymes are crucial for cell health, they place a heavy tax on mitochondria by depleting levels of NAD+. In the case of excessive oxidative stress and DNA damage, programmed cell death is initiated by lack of NAD+.

If you or someone you know is suffering from a degenerative nervous system condition, call SFNM today where a customized protocol and treatment plan will be put together for you! 

The following abstracts show the research behind NAD+ for these neurodegenerative conditions:
1. Therapeutic Approach to PD
2. Mitochondrial Metabolism for PD
3. Stroke Recovery with NAD
4. NADH As Treatment for AD
5. AD Therapy Targeting Mitochondria

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Dr. Jillian Shannon has a general naturopathic practice and specializes in regenerative medicine including BHRT, joint injections and IV therapies. She has been working closely with other practitioners specializing in functional endocrinology and anti-aging medicine with the use of stem cells, ozone, and PRP. She is available full time at SFNM and is accepting new patients.